Drug Lord 2.0
Your goal is still to amass as much money as possible by buying and selling drugs, but your neighborhood has grown considerably.
You can now vist major world cities via air travel to buy and sell goods. In some cities drugs are dirt cheap, and in others they are priced sky high. Watching the markets is your key to success in buying low and selling high.
All this globe-trotting is not without its dangers, however, airport security has a watchful eye open drug dealers, and unless you take precautions you might find yourself staring at the flashes from their guns.